HELIX Chromatography provides several options for Method Development Services. Experience scientists will be assigned to the project to develop your methods. We will sign a Non-Disclosure Agreement if your company requires this. Once we have details for your separation we can estimated the time required for the method and let you know when we can start on your project. You have the right to reject our recommendation and decide on your own what service to use. Once we develop a method we will ask you to review it and let us know if anything else needs to be done. We will use our columns to develop a method, but there is no obligation to buy any columns.

We try to start method development within two days of receiving samples, but we can also accommodate rush requests. If we have the required compounds in our library we can use them to develop a method for you, otherwise you’ll need to provide samples and standards. Providing us with samples that are not in solution can help us develop method much faster. We require 5-10 mg of each standard/marker. We require submission of standards or markers to identify peaks in your specific mixture.

We provide various tiers of service:

  1. Basic Free MDS. The basic free screening method development includes screening done with 2 columns and 2 different mobile phase. Total time allowance will not exceed 3 hours, and will be scheduled as time permits. Chromatograms and raw data may be provided if needed. We reserve the right to terminate the project if the time is exceeded, or ask customer to move to a paid tier. Customer is updated when project is completed.
  2. Silver MDS. Paid Method Development Services. Screening as many as 5 columns with 3 mobile phases. Total time allowance is 8 hours at $125/h. Daily updates on the project upon request. After 8 hours the customer has a choice to terminate the project or move to the next tier option. Providing chromatograms in PowerPoint/PDF format, and raw data per request.
  3. Gold MDS. Paid Extended Method Development Services. Includes finding optimum conditions achieving desired and specified resolution between compounds. Time allowance is up to 40 hours at $125/h. After 40 hours customer has a choice to terminate the project or move to the next tier option. Daily updates on the project upon request. Providing report, chromatograms, raw data and recommendations.
  4. Diamond MDS. Pre-Validation Method Development Services. Includes finding optimum conditions, achieving desired and specified resolution between compounds. Testing 3 different lots of columns to provide reproducibility data. Conducting quantitation and linearity studies. Time allowance varies on the project. Daily updates on the project upon request. Providing report, chromatograms, raw data and recommendations. 30% discount for the first 3 columns upon receiving the payment for method development

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