Fast HPLC Analysis of Three Drugs on Coresep 100 Mixed-Mode Core-Shell Column

Conditions of Experiment
Column: Coresep 100
Separation Modes: reversed-phase and cation-exchange
Column Dimenstions: 3.2 x 100 mm, 2.7 um, 90A
Mobile Phase: MeCN from 30% to 60% in 8 min, 0.05% TFA
Detection: UV 275 nm
Sample: 0.1-0.3 mg/ml
Injection: 1 uL
Flow rate: 0.8 mL/min
Class of compounds: Aromatic acid, Catecholamine, Drug, Neurotransmitter, Pyridine
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Polar
Compounds: Phenylephrine, Naproxen, Loratadine