MM Reversed-Phase and HILIC Mixed-Mode Method Development Kits

MM Reversed-Phase and HILIC Mixed-Mode Method Development Kits example

 

MM Reversed-Phase and HILIC Fast Screening Kit “RP&HILIC-FS Kit” (set of 50 mm columns)

MM Reversed-Phase and HILIC High Resolution Kit “RP&HILIC-HR Kit” (set of 150 mm columns)

MM Reversed-Phase and HILIC Screen and Resolve Kit “RP&HILIC-SR KIt” (set of 50 mm and 150 mm columns)

 

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  1. Amaze TH – a tri-modal column with HILIC, strong cation-exchange and strong anion-exchange properties, based on ultrapure spherical silica gel, based on ultrapure spherical silica gel. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic compounds in HILIC, cation- and anion-exchange, cation- and anion-exclusion modes. Effective in analysis of metabolomic compounds. Analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run. Can be used in the analysis of lipids.
  2. Amaze HD – a bi-modal column with HILIC and strong cation-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic in HILIC, cation-exchange, and anion-exclusion modes. Effective in analysis of metabolomic compounds. Analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run.
  3. Heritage MA – a bi-modal column with both reversed-phase and strong anion-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophobic basic, hydrophobic neutral, hydrophilic acidic, hydrophilic acidic small molecules and medium size molecules. Retains and separates basic polymers in RP/cation-exclusion and size-exclusion modes. Analysis of hydrophobic basic drugs and acidic counter-ions in one run. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.
  4. Coresep 100 – a bi-modal column with reversed-phase and medium strength cation-exchange properties, based on core-shell particles. Designed to retain hydrophobic neutral, hydrophobic acidic, hydrophobic zwitterionic and hydrophilic basic compounds. Analysis of hydrophobic acidic drugs and basic hydrophilic counterions. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.
  5. Coresep SB – a bi-modal column with reversed-phase and strong anion-exchange properties based on core-shell particles. Designed to retain and separate hydrophobic basic, hydrophobic neutral, hydrophilic acidic, hydrophilic acidic small molecules and medium size molecules. Retains and separates basic polymers in RP/cation-exclusion and size exclusion modes. Analysis of basic hydrophobic drugs and acidic counter-ions in one run. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.

 

Application Examples:

HPLC Analysis of Sugars, Amino Acids and Carboxylic Acids on Amaze TH Mixed-Mode Column

HPLC Analysis of Glucose, Glucuronic and Gluconic Acids on Amaze TH Mixed-Mode Column

Simultaneous HPLC Analysis of Sodium Ion and Sulfate Ion on Amaze TH Mixed-Mode Column

HPLC Analysis of 18 Underivatized Amino Acids on Amaze HD Mixed-Mode Column

HPLC Method for Analysis of Nucleosides and Nucleoside Derivatives on Amaze HD Column

HPLC Analysis of Glyphosate and Related Products on Heritage MA Mixed-Mode Column

HPLC Analysis of Nitrite and Nitrate Ions on Heritage MA Mixed-Mode Column

Baseline HPLC Separation of 22 Acidic, Basic and Neutral Pesticides and Antibiotics on Coresep 100 Mixed-Mode Column

Fast HPLC Analysis of Drug Composition on Coresep 100 Mixed-Mode Core-Shell Column

HPLC Analysis of Ethanolamines on Coresep 100 Mixed-Mode Column
HPLC Analysis of Isomers of Toluidine on Core-Shell Mixed-Mode Coresep 100 Column

HPLC Separation of Underivatized Amino Acids in Buffer-Less Mode on Coresep 100 Core-Shell Mixed-Mode Column

HPLC Analysis of Ascorbic and Dehydroascorbic Acids on Coresep SB Column in Reversed-Phase Anion-Exchange Modes

HPLC Analysis of Hydrophilic Acids on Coresep SB Column in Reversed-Phase and Anion-Exchange Modes

HPLC Analysis of Dextromethorphan and Counter-Ion on Coresep SB Column in Reversed-Phase Mixed Mode

OTHER APPLICATIONS