HILIC Mixed-Mode Method Development Kits

HILIC Mixed-Mode Method Development Kits example

 

HILIC MM Fast Screening Kit “HILIC-FS Kit” (set of 50 mm columns)

HILIC MM High Resolution Kit “HILIC-HR Kit” (set of 150 mm columns)

HILIC MM Screen and Resolve Kit “HILIC-SR Kit” (set of 50 mm and 150 mm columns)

 

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  1. Amaze TH – a tri-modal column with HILIC, strong cation-exchange and strong anion-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic compounds in HILIC, cation- and anion-exchange, cation- and anion-exclusion modes. Effective in analysis of metabolomic compounds. Analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run. Can be used in the analysis of lipids.
  2. Amaze HD – a bi-modal column with HILIC and strong cation-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic in HILIC, cation-exchange, and anion-exclusion modes. Effective in analysis of metabolomic compounds. Analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run.
  3. Amaze HA – a bi-modal column with strong HILIC and strong anion-exchange properties, based on ultrapure spherical silica gel. Has some reversed-phase properties and can be used for analysis of lipids. Designed to retain and separate hydrophilic acidic, hydrophobic acidic compounds, inorganic and organic anions in HILIC, RP, anion-exchange and cation-exclusion modes.
  4. Coresep S – a bi-modal column with HILIC and medium strength cation-exchange properties, based on core-shell silica gel particles. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic compounds in HILIC, cation-exchange, and anion-exclusion modes. Effective in analysis of metabolomic compounds. Analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run. Can be used in the analysis of lipids.
  5. Heritage N – a bi-modal column with HILIC and weak cation-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophilic neutral, hydrophilic acidic and basic, zwitterionic compounds in HILIC, cation-exchange, and anion-exclusion modes. Effective in analysis of metabolomic compounds. Analysis of hydrophilic and hydrophobic drugs and counter-ions in the same run. Can be used in the analysis of lipids.

 

Application Examples:

HPLC Analysis of Sugars, Amino Acids and Carboxylic Acids on Amaze TH Mixed-Mode Column

HPLC Analysis of Glucose, Glucuronic and Gluconic Acids on Amaze TH Mixed-Mode Column

Simultaneous HPLC Analysis of Sodium Ion and Sulfate Ion on Amaze TH Mixed-Mode Column

HPLC Analysis of 18 Underivatized Amino Acids on Amaze HD Mixed-Mode Column

HPLC Method for Analysis of Nucleosides and Nucleoside Derivatives on Amaze HD Column

HPLC Separation of Phosphate, Thiophosphate and Sodium Ions on Amaze HA Mixed-Mode Column

HPLC Analysis of Underivatized Amino Acids on Coresep S Column in HILIC and Cation-Exchange Modes

HPLC Analysis of Ascorbic, Methylmalonic and Succinic Acids on Heritage N Column

HPLC Analysis of Pseudoephedrine and Citric Acid on Heritage N Column

OTHER APPLICATIONS