Reversed-phase Mixed-Mode Method Development Kits

Reversed-phase Mixed-Mode Method Development Kits example

 

Reversed-Phase MM Fast Screening Kit “RP-FS Kit” (set of  50 mm columns)

Reversed-Phase MM High Resolution Kit “RP-HR Kit” (set of 150 mm columns)

Reversed-Phase MM Screen and Resolve Kit RP-SR KIt (set of 50 mm and 150 mm columns)

 

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  1. Amaze SA – a tri-modal column with both reversed-phase, weak pi-pi functionalities and strong cation-exchange properties, based on ultrapure spherical silica gel. Designed to retain hydrophobic neutral, hydrophobic acidic, hydrophobic zwitterionic and hydrophilic basic compounds. Analysis of hydrophobic acidic drugs and basic hydrophilic counterions. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.
  2. Amaze TR – a tri-modal column with reversed-phase, weak cation-exchange and weak anion-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophobic basic, hydrophobic acidic, hydrophobic zwitterionic, hydrophilic neutral, hydrophilic acidic and hydrophilic basic compounds. Effective in separation of ionizable structural isomers. Analysis of basic and acidic drugs and corresponding counter-ions. MS-compatible mobile phases.
  3. Coresep 100 – a bi-modal column with reversed-phase and medium strength cation-exchange properties, based on core-shell particles. Designed to retain hydrophobic neutral, hydrophobic acidic, hydrophobic zwitterionic and hydrophilic basic compounds. Analysis of hydrophobic acidic drugs and basic hydrophilic counterions. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.
  4. Coresep SB – a bi-modal column with reversed-phase and strong anion-exchange properties based on core-shell particles. Designed to retain and separate hydrophobic basic, hydrophobic neutral, hydrophilic acidic, hydrophilic acidic small molecules and medium size molecules. Retains and separates basic polymers in RP/cation-exclusion and size exclusion modes. Analysis of basic hydrophobic drugs and acidic counter-ions in one run. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.
  5. Heritage MA -a bi-modal column with both  reversed-phase and strong anion-exchange properties, based on ultrapure spherical silica gel. Designed to retain and separate hydrophobic basic, hydrophobic neutral, hydrophilic acidic, hydrophilic acidic small molecules and medium size molecules. Retains and separates basic polymers in RP/cation-exclusion and size-exclusion modes. Analysis of hydrophobic basic drugs and acidic counter-ions in one run. Effective in separation of ionizable structural isomers. MS-compatible mobile phases.

 

Application Examples:

HPLC Analysis of Zwitterions DOTA and DO3A om Amaze SA Mixed-Mode Column

HPLC Separation of Hydrophobic, Hydrophilic, Basic and Acidic Compounds on Amaze TR Mixed-Mode Column

HPLC Separation of Acidic Drugs Naproxen, Ketoprofen, Ibuprofen and Basic Counterion on Amaze TR Tri-Modal Column

HPLC Separation of Glyphosate and Paraquat on Amaze TR Mixed-Mode Column

Baseline HPLC Separation of 19 Acidic, Basic and Neutral Pesticides and Antibiotics on Coresep 100 Mixed-Mode Column

HPLC Separation of Neurotransmitters on Coresep 100 Column in Reversed-Phase and Cation-Exchange Modes

Ultra-Fast HPLC Separation of Underivatized Amino Acids in Reversed-Phase and Cation-Exchange Modes

HPLC Analysis of Dextromethorphan and Counter-Ion on Coresep SB Column in Reversed-Phase Mixed Mode

HPLC Analysis of Ascorbic and Dehydroascorbic Acids on Coresep SB Column in Reversed-Phase Anion-Exchange Modes

HPLC Analysis of Hydrophilic Acids on Coresep SB Column in Reversed-Phase and Anion-Exchange Modes

HPLC Separation of Nine Nucleotides on Coresep SB Core-Shell Mixed-Mode Column
Simultaneous HPLC Analysis of Brompheniramine and Maleic Acid Couner-Ion on Heritage MA Mixed-Mode Column

HPLC Analysis of Seven Anions on Heritage MA Mixed-Mode Column

HPLC UV Analysis of Polyethyleneimine on Heritage MA Column in Ion-Exclusion and Size-Exclusion Modes

OTHER APPLICATIONS