HPLC Analysis of Dextromethorphan and Related Impurities on Amaze SC Mixed-Mode Column
Conditions of Experiment
Column: | Amaze SC |
Separation Modes: | reversed-phase, cation-exchange |
Column Dimenstions: | 3.0x100 mm, 3 um, 100A |
Mobile Phase: | ACN/Water/Ammonium phosphate gradient |
Detection: | 280 nm |
Sample: | 0.1-0.3 mg/ml |
Injection: | 5 uL |
Flow rate: | 0.6 ml/min |
Analytes
Class of compounds: | Amines, Aromatic base, Drug |
Nature of compounds: | Basic, Hydrophilic, Hydrophobic |
Compounds: | Ent-3-Methoxymorphinan, ent-(14S)-3-Methoxy-17-Methylmorphinian, 10-Keto dextromethorphan, Dextromethorphan |