HPLC Analysis of Drug Alprazolam and Related Impurities on Core-Shell Mixed-Mode Coresep 100 Column

HPLC Analysis of Drug Alprazolam and Related Impurities on Core-Shell Mixed-Mode Coresep 100 Column
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Conditions of Experiment
Column: Coresep 100
Separation Modes: reversed-phase and cation-exchange
Column Dimenstions: 3.2 x 100 mm, 2.7 um, 90A
Mobile Phase: MeCN 40% with 30 mM AmFm pH 3
Detection: UV 255 nm
Sample: 0.3 mg/ml
Injection: 1 uL
Flow rate: 0.6 mL/min
Analytes
Class of compounds: Aromatic base, Drug
Nature of compounds: Basic, Hydrophobic
Compounds: Alprazolam