2-Naphthoic acid and related impurities were analyzed on Coresep SB mixed-mode column. Method is fast, robust, reproducible, and can be used for analysis of 2-naphthoic acid and other organic acids in various sample matrices by mixed-mode reversed-phase anion-exchange chromatography. Various mobile phases can be used with Coresep SB column to accommodate different detection techniques (UV, MS, CAD, ELSD detection). Other compounds can be retained and separated on this mixed-mode column if they are hydrophobic and acidic in nature. Core-shell mixed-mode columns provide a great combination of unique selectivity, speed, and efficiency.
|Separation Modes:||reversed-phase and anion-exchange|
|Column Dimenstions:||3.0 x 100 mm|
|Mobile Phase:||40% ACN with 120 mM AmFm pH 3|
|Detection:||UV 255 nm|
|Flow rate:||0.6 mL/min|
|Class of compounds:||Aromatic acid, Organic acid|
|Nature of compounds:||Acidic, Hydrophobic|