Aspirin
Aspirin
Aspirin
Select Applications
Direct HPLC Analysis of Acidic Drug Aspirin in Human Blood on Heritage MA Mixed-Mode Column
HPLC Analysis of Five Acidic Drugs on Heritage MA Mixed-Mode Column
HPLC Analysis of Six Drugs on Reversed-Phase Aromatic Phases. Selectivity Adjustment
HPLC Analysis of Six Drugs on Reversed-Phase Aromatic Phases. Relative Selectivity
HPLC Analysis of Excedrin Pain Medication on Reversed-Phase Aromatic Phases
HPLC Analysis of 6 Aromatic Acidic, Zwitterionic and Neutral Compounds on Amaze Aromatic Stationary Phases
HPLC Analysis of Drug Composition on Heritage C18 Column According to US Pharmacopeia
Direct HPLC Analysis of Acidic Drug Aspirin in Human Blood on Heritage MA Mixed-Mode Column
Conditions of Experiment
Column: | Heritage MA |
Separation Modes: | anion-exchange |
Column Dimenstions: | 4.6x150 mm, 3 um, 100A |
Mobile Phase: | 75% ACN with 15 mM AmAc pH 4 |
Detection: | 235 nm |
Sample: | 0.1 mg/ml |
Injection: | 1 uL |
Flow rate: | 1 ml/min |
Analytes
Class of compounds: | Aromatic acid, Drug |
Nature of compounds: | Hydrophobic, Neutral, Polar |
Compounds: | Aspirin |
HPLC Analysis of Five Acidic Drugs on Heritage MA Mixed-Mode Column
Conditions of Experiment
Column: | Heritage MA |
Separation Modes: | reversed-phase and anion-exchange |
Column Dimenstions: | 4.6x150 mm, 3 um, 100A |
Mobile Phase: | 35% ACN with 0.15% sulfuric acid |
Detection: | 255 nm |
Sample: | 0.2-0.4 mg/ml |
Injection: | 2 uL |
Flow rate: | 1 ml/min |
Analytes
Class of compounds: | Aromatic acid, Drug, Organic acid |
Nature of compounds: | Acidic, Hydrophilic, Hydrophobic, Neutral, Polar |
Compounds: | Aspirin, Salicylic acid, Ketoprofen, Naproxen, Ibuprofen |
HPLC Analysis of Six Drugs on Reversed-Phase Aromatic Phases. Selectivity Adjustment
Conditions of Experiment
Column: | Amaze C18 |
Separation Modes: | reversed-phase |
Column Dimenstions: | 4.6x250 mm, 5 um, 100A |
Mobile Phase: | 0% ACN with 0.15% phosphoric acid |
Detection: | 255 nm |
Sample: | 0.2-0.6 mg/ml |
Injection: | 2 uL |
Flow rate: | 1 ml/min |
Analytes
Class of compounds: | Aromatic acid, Aromatic base, Drug, Pyridine |
Nature of compounds: | Acidic, Basic, Hydrophilic, Hydrophobic, Neutral, Polar |
Compounds: | Aspirin, Albuterol, Naproxen, Propranolol, Ibuprofen, Pyrilamine |
HPLC Analysis of Six Drugs on Reversed-Phase Aromatic Phases. Relative Selectivity
Conditions of Experiment
Column: | Amaze C18 |
Separation Modes: | reversed-phase |
Column Dimenstions: | 4.6x250 mm, 5 um, 100A |
Mobile Phase: | 0% ACN with 0.15% phosphoric acid |
Detection: | 255 nm |
Sample: | 0.2-0.6 mg/ml |
Injection: | 2 uL |
Flow rate: | 1 ml/min |
Analytes
Class of compounds: | Aromatic acid, Aromatic base, Drug, Pyridine |
Nature of compounds: | Acidic, Basic, Hydrophilic, Hydrophobic, Neutral, Polar |
Compounds: | Aspirin, Albuterol, Naproxen, Propranolol, Ibuprofen, Pyrilamine |
HPLC Analysis of Excedrin Pain Medication on Reversed-Phase Aromatic Phases
Conditions of Experiment
Column: | Amaze C18 |
Separation Modes: | reversed-phase |
Column Dimenstions: | 4.6x150 mm, 3 um, 100A |
Mobile Phase: | 25% ACN with 50 mM ammonium phosphate and 0.1% phosphoric acid |
Detection: | 220 nm |
Sample: | 0.3-0.5 mg/ml |
Injection: | 1 uL |
Flow rate: | 1 ml/min |
Analytes
Class of compounds: | Aromatic acid, Aromatic compound, Drug, Stimulant, Xanthine |
Nature of compounds: | Hydrophilic, Hydrophobic, Neutral, Polar |
Compounds: | Acetaminophen, Caffeine, Aspirin |
HPLC Analysis of 6 Aromatic Acidic, Zwitterionic and Neutral Compounds on Amaze Aromatic Stationary Phases
Application description
Comparison run on Amaze PFP, Amaze AR, Amaze SPF, and Heritage C20 columns.
Conditions of Experiment
Column: | Amaze AR |
Separation Modes: | reversed-phase, pi-pi |
Column Dimenstions: | 4.6x150 mm, 5 μm, 100A |
Mobile Phase: | 28% ACN with 20 mM AmAc pH 4.5 |
Detection: | UV 255 nm |
Sample: | 1 mg/ml |
Injection: | 3 μL |
Flow rate: | 1 ml/min |
Analytes
Class of compounds: | Amino acid, Aromatic acid, Aromatic compound, Drug, Isomer, Organic acid, Preservative, Stimulant, Xanthine |
Nature of compounds: | Acidic, Hydrophilic, Hydrophobic, Neutral, Polar, Zwitterionic |
Compounds: | Caffeine, 4-Aminobenzoic acid, Aspirin, 4-Hydroxybenzoic acid, Sorbic acid, Benzoic acid |
HPLC Analysis of Drug Composition on Heritage C18 Column According to US Pharmacopeia
Conditions of Experiment
Column: | Heritage С18 |
Separation Modes: | reversed-phase |
Column Dimenstions: | 4.6 x 100 mm, 5 um, 100A |
Mobile Phase: | MeOH/H2O/AcOH 30/67/3 |
Detection: | UV 275 nm |
Sample: | 0.2 mg/ml |
Injection: | 5 uL |
Flow rate: | 1 mL/min |
Analytes
Class of compounds: | Aromatic acid, Aromatic compound, Drug, Organic acid, Stimulant, Xanthine |
Nature of compounds: | Acidic, Hydrophilic, Hydrophobic, Neutral, Polar |
Compounds: | Acetaminophen, Caffeine, Aspirin, Benzoic acid, Salicylic acid |