Dimethylformamide
HPLC Analysis of DMF and N-Nitrosodimethylamine in Metformin Drug on Heritage MC Mixed-Mode Column
Conditions of Experiment
Column: | Heritage MC |
Separation Modes: | reversed-phase, cation-exchnge |
Column Dimenstions: | 3.0x100 mm, 3 μm, 100A |
Mobile Phase: | ACN/Water/Formic acid gradient |
Detection: | UV 230 nm |
Sample: | 1 mg/ml |
Injection: | 2μL |
Flow rate: | 0.6 ml/min |
Analytes
Class of compounds: | Drug, Organic compound, Organic solvent |
Nature of compounds: | Basic, Hydrophilic, Neutral, Polar |
Compounds: | N-Nitrosodimethylamine, Dimethylformamide, Metformin |
HPLC Analysis of DMF and N-Nitrosodimethylamine on Amaze HD Mixed-Mode Column
Conditions of Experiment
Column: | Amaze HD |
Separation Modes: | HILIC, cation-exchange |
Column Dimenstions: | 3.0x100 mm, 3 μm, 100A |
Mobile Phase: | ACN/water/Ammonium formate |
Detection: | UV 230 nm |
Sample: | 1 mg/ml |
Injection: | 2 μL |
Flow rate: | 0.6 ml/min |
Analytes
Class of compounds: | Drug, Organic compound, Organic solvent |
Nature of compounds: | Basic, Hydrophilic, Neutral, Polar |
Compounds: | N-Nitrosodimethylamine, Dimethylformamide, Metformin |
HPLC Analysis of Dimethylformamide and Dimethylacetamide on Coresep 100 Column
Conditions of Experiment
Column: | Coresep 100 |
Separation Modes: | reversed-phase |
Column Dimenstions: | 4.6 x 150 mm |
Mobile Phase: | 2% ACN with 0.2% phosphoric acid |
Detection: | UV 230 nm |
Sample: | 0.3 mg/ml |
Injection: | 3 uL |
Flow rate: | 1 mL/min |
Analytes
Class of compounds: | Organic solvent |
Nature of compounds: | Hydrophilic, Neutral, Polar |
Compounds: | Dimethylformamide, Dimethylacetamide |