Ibuprofen

HPLC Analysis of Acidic Drugs, Monovalent and Divalent Basic Counterions on Amaze SC Mixed-Mode Column
Conditions of Experiment
Column: Amaze SC
Separation Modes: reversed-phase, cation-exchange and anion-exclusion
Column Dimenstions: 3.0x100 mm, 5 μm, 100A
Mobile Phase: 30% ACN wiith 70 mM AmFm pH 3
Detection: UV 255 nm, ELSD
Sample: 0.3 mg/ml
Injection: 2 μL
Flow rate: 0.6 ml/min
Analytes
Class of compounds: Aromatic acid, Drug, Inorganic anion, Inorganic cation
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Polar
Compounds: Sodium ion, Potassium ion, Magnesium ion, Barium ion, Ketoprofen, Naproxen, Ibuprofen
HPLC Analysis of Acidic Drug Ibuprofen and Basic Counterions on Amaze SC Mixed-Mode Column
Conditions of Experiment
Column: Amaze SC
Separation Modes: reversed-phase, cation-exchange and anion-exclusion
Column Dimenstions: 3.0x100 mm, 5 μm, 100A
Mobile Phase: 35% ACN wiith 30 mM AmFm pH 3
Detection: UV 255 nm, ELSD
Sample: 0.3 mg/ml
Injection: 2 μL
Flow rate: 0.6 ml/min
Analytes
Class of compounds: Aromatic acid, Drug, Inorganic cation
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Polar
Compounds: Sodium ion, Potassium ion, Ibuprofen
HPLC Separation of Acidic Drugs Naproxen, Ketoprofen, Ibuprofen and Basic Counterion Sodium
Conditions of Experiment
Column: Amaze TR
Separation Modes: Reversed-phase, cation-exchange, anion-exchange
Column Dimenstions: 3.0x100 mm, 3 um, 100A
Mobile Phase: 70% ACN with 10 mM AmAc pH 5
Detection: UV 275 nm ELSD
Sample: 0.5 mg/ml
Injection: 3 uL
Flow rate: 0.6 ml/min
Analytes
Class of compounds: Aromatic acid, Drug, Inorganic cation
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Polar
Compounds: Sodium ion, Naproxen, Ketoprofen, Ibuprofen
HPLC Analysis of Drug Ibuprofen on Heritage C18 Column According to US Pharmacopeia
Conditions of Experiment
Column: Heritage С18
Separation Modes: reversed-phase
Column Dimenstions: 4.6 x 250 mm, 5 um, 100A
Mobile Phase: 0.1% H3PO4 / MeCN (45/55)
Detection: UV 254 nm
Sample: 0.3 mg/ml
Injection: 5 uL
Flow rate: 1 mL/min
Analytes
Class of compounds: Aromatic acid, Aromatic compound, Drug
Nature of compounds: Acidic, Hydrophobic, Neutral
Compounds: Benzophenone, Ibuprofen