N-Nitrosodimethylamine

HPLC Analysis of DMF and N-Nitrosodimethylamine in Metformin Drug on Heritage MC Mixed-Mode Column
Conditions of Experiment
Column: Heritage MC
Separation Modes: reversed-phase, cation-exchnge
Column Dimenstions: 3.0x100 mm, 3 μm, 100A
Mobile Phase: ACN/Water/Formic acid gradient
Detection: UV 230 nm
Sample: 1 mg/ml
Injection: 2μL
Flow rate: 0.6 ml/min
Analytes
Class of compounds: Drug, Organic compound, Organic solvent
Nature of compounds: Basic, Hydrophilic, Neutral, Polar
Compounds: N-Nitrosodimethylamine, Dimethylformamide, Metformin
HPLC Analysis of DMF and N-Nitrosodimethylamine on Amaze HD Mixed-Mode Column
Conditions of Experiment
Column: Amaze HD
Separation Modes: HILIC, cation-exchange
Column Dimenstions: 3.0x100 mm, 3 μm, 100A
Mobile Phase: ACN/water/Ammonium formate
Detection: UV 230 nm
Sample: 1 mg/ml
Injection: 2 μL
Flow rate: 0.6 ml/min
Analytes
Class of compounds: Drug, Organic compound, Organic solvent
Nature of compounds: Basic, Hydrophilic, Neutral, Polar
Compounds: N-Nitrosodimethylamine, Dimethylformamide, Metformin
HPLC Analysis of N-Nitrosodimethylamine and N-Nitrosodiethylamine on Coresep SB Mixed-Mode Columns
Conditions of Experiment
Column: Coresep SB
Separation Modes: reversed-phase
Column Dimenstions: 4.6x150 mm, 2.7 um, 90A
Mobile Phase: 5% ACN with 0.1% acid
Detection: UV 230 nm
Sample: 1 mg/ml
Injection: 3 uL
Flow rate: 1 ml/min
Analytes
Class of compounds: Organic compound
Nature of compounds: Basic, Hydrophilic, Neutral, Polar
Compounds: N-Nitrosodimethylamine, N-Nitrosodiethylamine