Propranolol

HPLC Analysis of Six Drugs on Reversed-Phase Aromatic Phases. Selectivity Adjustment
Conditions of Experiment
Column: Amaze C18
Separation Modes: reversed-phase
Column Dimenstions: 4.6x250 mm, 5 um, 100A
Mobile Phase: 0% ACN with 0.15% phosphoric acid
Detection: 255 nm
Sample: 0.2-0.6 mg/ml
Injection: 2 uL
Flow rate: 1 ml/min
Analytes
Class of compounds: Aromatic acid, Aromatic base, Drug, Pyridine
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Neutral, Polar
Compounds: Aspirin, Albuterol, Naproxen, Propranolol, Ibuprofen, Pyrilamine
HPLC Analysis of Six Drugs on Reversed-Phase Aromatic Phases. Relative Selectivity
Conditions of Experiment
Column: Amaze C18
Separation Modes: reversed-phase
Column Dimenstions: 4.6x250 mm, 5 um, 100A
Mobile Phase: 0% ACN with 0.15% phosphoric acid
Detection: 255 nm
Sample: 0.2-0.6 mg/ml
Injection: 2 uL
Flow rate: 1 ml/min
Analytes
Class of compounds: Aromatic acid, Aromatic base, Drug, Pyridine
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Neutral, Polar
Compounds: Aspirin, Albuterol, Naproxen, Propranolol, Ibuprofen, Pyrilamine
HPLC UV Analysis of Four Basic Drugs and Six Acidic Counterions on Heritage MA Mixed-Mode Column
Conditions of Experiment
Column: Heritage MA
Separation Modes: reversed-phase, anion-exchange, cation-exclusion
Column Dimenstions: 4.6x150 mm, 3 um, 100A
Mobile Phase: ACN/Water/Ammonium Phosphate pH 2.2
Detection: 205 nm
Sample: 0.2-0.5 mg/ml
Injection: 2 uL
Flow rate: 1 ml/min
Analytes
Class of compounds: Acidic counterion, Amines, Aromatic base, Aromatic compound, Drug, Inorganic anion, Organic acid, Sugar
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Polar
Compounds: Chlorpheniramine, Brompheniramine, Acetic acid, Lactic acid, Iodide ion, Succinic acid, Malic acid, Saccharic acid, Propranolol, Dextromethorphan
HPLC Separation of Hydrophobic, Hydrophilic, Basic and Acidic Compounds on Amaze TR Mixed-Mode Column
Conditions of Experiment
Column: Amaze TR
Separation Modes: RP, cation-exchange, anion-exchange
Column Dimenstions: 4.6x150 mm, 5 um, 100A
Mobile Phase: 30% ACN with 30 mM AmAc pH 5
Detection: UV 275 nm
Sample: 0.2-0.3 mg/ml
Injection: 3 uL
Flow rate: 1 ml/min
Analytes
Class of compounds: Aromatic base, Aromatic compound, Catecholamine, Drug, Neurotransmitter, Organic acid, Organic compound, Preservative, Stimulant
Nature of compounds: Acidic, Basic, Hydrophilic, Hydrophobic, Neutral, Polar
Compounds: Norphenylephrine, Ephedrine, 3,4-Dihydroxybenzoic acid, Benzenesulfonic acid, Propylparaben, Propranolol
HPLC Analysis of Drugs Procainamide and Propranolol on Heritage C18 Column According to US Pharmacopeia
Conditions of Experiment
Column: Heritage С18
Separation Modes: reversed-phase
Column Dimenstions: 4.6 x 250 mm
Mobile Phase: Water/MeOH/MeCN (30/30/40) with 10 m sodium dodecyl sulfonate and 10 mM Phosphoric acid
Detection: UV 254 nm
Sample:
Injection:
Flow rate: 1 mL/min
Analytes
Class of compounds: Aromatic base, Drug
Nature of compounds: Basic, Hydrophobic
Compounds: Procainamide, Propranolol